PTCB PTCE Pharmacy Technician Certification (CPhT) Exam Practice Test

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Total 223 questions
Question 1

The master formulation record is used to help:



Answer : A

AMaster Formulation Record (MFR)is adetailed document used in compounding pharmaciesto ensureconsistency, accuracy, and quality controlin preparing compounded medications.

An MFR includes:

Ingredients & amounts required.

Compounding procedures.

Stability and beyond-use dating (BUD).

Storage and labeling instructions.

This ensures that each compounded preparationmeets quality standardsand ismade correctly every time.

B . Prevent drug diversionIncorrect

Drug diversion prevention involves security measures, inventory control, and trackingcontrolled substances, not MFRs.

C . Eliminate patient profilesIncorrect

Patient profiles are essential for tracking medication history; MFRs are unrelated.

D . Guarantee drug availabilityIncorrect

MFRs do not affect drug supply; they ensure accurate compounding.

USP <795> (Non-Sterile Compounding Guidelines)-- RequiresMaster Formulation Records for all compounded preparations.

PTCB PTCE Exam Content Outline-- Covers compounding procedures and quality control measures.

Why Not the Other Options?Key Reference:


Question 2

A patient fills a prescription for a 30-day supply of amlodipine 10 mg. Two days later, the patient brings in a prescription for diltiazem 30 mg from their primary careprovider. Which of the following rejection messages is the pharmacy technician most likely to receive?



Answer : B

Amlodipine(10 mg) anddiltiazem(30 mg) are bothcalcium channel blockers (CCBs)used to treat hypertension and angina.

When a patient is prescribed two medications from the same therapeutic class, the pharmacy's prescription processing system may flag this as'therapeutic duplication.'

This alert is meant toprevent potential adverse effectssuch as excessive lowering of blood pressure or heart rate.

A . Prior authorization required Not applicable unless the insurance requires special approval before covering the drug.

C . NDC not covered Would appear if the specific drug product (based on its National Drug Code) is not covered by insurance, but this scenario relates to duplication, not coverage.

D . Refill too soon This applies to refilling a medication before the allowed time frame, but the scenario describes a new prescription.

PTCB PTCE Exam Content Outline -- Drug Interactions and Therapeutic Duplication

Lexicomp and Micromedex Drug Databases-- Reference sources for drug classifications.

ISMP Guidelines on Preventing Therapeutic Duplication Errors

Why Other Answers Are Incorrect?Pharmacy Technician Reference:


Question 3

Thegeneric namefor5-FUis:



Answer : D

5-FU (Fluorouracil) is a chemotherapy drugused forcolon, breast, and skin cancers.

It is apyrimidine analogthatprevents cancer cell DNA replication.

Why Other Options Are Incorrect:

A . Fluocinonide?Topical corticosteroid for skin conditions.

B . Fluoxetine (Prozac)?SSRI antidepressant.

C . Fluocinolone?Topical corticosteroid.

Reference:National Cancer Institute Chemotherapy Guide, PTCB Oncology Medications.


Question 4

A pharmacy must report the theft or significant loss of which of the following medications to the Drug Enforcement Administration (DEA)?



Answer : A

TheDrug Enforcement Administration (DEA)requires that theft or significant loss ofcontrolled substancesbe reported usingDEA Form 106.

(A) PregabalinSchedule V (Controlled Substance -- Must be Reported to DEA)

Pregabalin (brand name:Lyrica) is classified as aSchedule V controlled substanceunder theControlled Substances Act (CSA).

Pharmacies must report its theft or significant loss to the DEA using DEA Form 106.

(B) PiroxicamNot a Controlled Substance -- No Reporting Required

Piroxicam is anonsteroidal anti-inflammatory drug (NSAID).

It isnot a controlled substance, so DEA reporting isnot requiredfor theft or loss.

(C) ProchlorperazineNot a Controlled Substance -- No Reporting Required

Prochlorperazine is anantiemetic and antipsychotic.

It isnot a controlled substance, so DEA reporting isnot requiredfor theft or loss.

(D) PioglitazoneNot a Controlled Substance -- No Reporting Required

Pioglitazone (brand name:Actos) is anantidiabetic medication (thiazolidinedione).

It isnot a controlled substance, so DEA reporting isnot requiredfor theft or loss.

Thepharmacist-in-charge (PIC)must fileDEA Form 106in the event of a significant loss or theft of anySchedule II--V controlled substance.

The loss must be reportedwithin one business dayto theDEAand local law enforcement.

Minor losses due to inventory miscounts do not require DEA reporting but should be documented internally.

DEA Controlled Substances Act (CSA): https://www.deadiversion.usdoj.gov/21cfr/21usc/

DEA Form 106 -- Reporting Theft/Loss of Controlled Substances: https://www.deadiversion.usdoj.gov/21cfr_reports/theft/

PTCB Exam Content Outline -- Pharmacy Laws & Regulations

Controlled Substance Classification of Each Drug:DEA Reporting Requirements for Pharmacy Technicians:Reference for Pharmacy Technicians:


Question 5

A patient who received90 tabletsone month ago contacts the pharmacy to request a refill. The insurance rejects the claim, saying that the refill is56 days too soon.The claim rejection is likely the result of submitting an incorrect:



Answer : A

Insurance requires accurate ''days supply'' calculations.If a30-daysupply is incorrectly entered as a90-daysupply, the system will reject early refills.

Reference:PTCE Pharmacy Billing and Reimbursement Guidelines.


Question 6

Which of the following medications is ahormonethat would be appropriate for pharmacies todispose of as hazardous waste?



Answer : C

Norethindrone is a synthetic progestin hormone found in oral contraceptives.

Hormones and chemotherapy drugs must be disposed of as hazardous pharmaceutical waste per EPA and USP <800> guidelines.

Reference:EPA Hazardous Drug Disposal Regulations, USP <800> Hazardous Drug List.


Question 7

The administration of ciprofloxacin tablets with milk could cause the inhibition of what pharmacokinetic process?



Answer : A

Ciprofloxacin is afluoroquinolone antibioticthat chelates (binds) withdivalent and trivalent cationssuch ascalciumfound in milk. This interaction forms aninsoluble complex, significantly reducing ciprofloxacin's absorption in the gastrointestinal (GI) tract, leading to decreased bioavailability and reduced therapeutic effect.

B . Distribution Incorrect; milk does not directly impact the distribution of ciprofloxacin in the bloodstream.

C . Metabolism Incorrect; ciprofloxacin is primarily metabolized in the liver, and milk does not inhibit its enzymatic breakdown.

D . Excretion Incorrect; ciprofloxacin is mainly excreted by the kidneys, and milk does not significantly impact this process.

Other Answer Choices Explained:Pharmacist's Recommendation:Patients should take ciprofloxacinat least 2 hours before or 6 hours afterconsuming dairy products to avoid reduced drug absorption.


PTCB PTCE Exam Content Outline (Pharmacokinetics & Pharmacodynamics)

Lexicomp Drug Interactions Database

FDA Ciprofloxacin Drug Label & Administration Guidelines

Goodman & Gilman's The Pharmacological Basis of Therapeutics

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Total 223 questions